Endocrine Abstracts

Introduction: Breast cancer is, by far, the most frequent cancer among women. Local and systemic factors have been shown to drive growth in breast cancer cells. There is increasing evidence that hormone ghrelin, known for the growth hormone releasing effect and food intake modulator, may also influence cancer growth. Ghrelin has been shown to be produced by some tumor cells, including breast cancer cells.Objective: To analyze ghrelin expression in correl...

Introduction: Ghrelin, a peptide hormone produced in the stomach, stimulates secretion of growth hormone and regulates appetite and energy homeostasis. Various other effects attributed to ghrelin may contribute to many aspects of cancer development and progression.Material and Methods: Using polyclonal antibody immunohistochemistry, we assessed (by intensity scoring) the immunolocalization of ghrelin in 70 tissue samples, and described particularities wi...